Focus Factor vs Prevagen: Which Is Right For you?

30th October 2023
Introduction - Helping You Choose The Right Brain Supplement
In this article we compare Focus Factor vs Prevagen, both are well-known brain supplements. Each offers a unique composition, purportedly tailored to bolster cognitive functionality. The former, Focus Factor, boasts an expansive list of ingredients ranging from essential vitamins and minerals like Vitamin A, D, C, B-complex, and trace elements like Zinc, Copper, and Magnesium to notable herbal extracts like Ginkgo Biloba and Grape Seed. Additionally, it incorporates amino acids such as L-Tyrosine and L-Glutamine, and nootropic compounds like Dimethylaminoethanol Bitartrate (DMAE) and L-Alpha Glycerophosphorylcholine (Alpha GPC).
Prevagen adopts a more streamlined approach. It highlights the inclusion of Vitamin D and the unique protein, Apoaequorin. Derived from certain jellyfish, Apoaequorin is postulated to assist in calcium regulation within the brain, potentially improving short-term memory and overall cognitive function. But how well do each they work?
Overall Results And Recommendation
Focus Factor
Overall Rating

Prevagen
Overall Rating

- Focus Factor Does a Few Things Well, But Overall It's A Basic Offering: Limited range and level of benefits, often not meeting broad cognitive needs. Many ingredients are dosed below clinically effective levels.
- Prevagen Lacks Scientific Evidence And Results Were Disappointing: In our testing, most users reported no discernable cognitive improvement after consistent usage. Prevagen's ingredient profile is very limited and lacks many clinically proven cognitive enhancing ingredients. Instead, it relies on Apoaequorin, an ingredient lacking in robust scientific evidence for its effectiveness as a cognitive enhancer.
- Recommended Alternative: In our testing, NooCube outperformed Focus Factor and Prevagen in all areas. Its more comprehensive formulation is backed by scientific evidence, and we found it offered a far greater level of improvement to focus, cognitive performance and memory.
NooCube
Overall Rating

Quick Decision Guide - Focus Factor vs Prevagen vs Leading Nootropic (NooCube)
CRITERIA | Focus Factor ![]() | Prevagen ![]() | NooCube ![]() |
---|---|---|---|
Overall Rating (From Our Experience Using Each Product) | 54%
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| 28%
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| 92%
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|
Main Benefits | Focused on cognitive function | Experimental and willing to try a novel ingredient | Comprehensive cognitive improvement with a multi-ingredient blend |
Scientific Backing | Moderate, proven ingredients but at too low dosages | Limited, especially for Apoaequorin | Strong, with many well-researched ingredients |
Formula Complexity | Complex | Minimalistic | Comprehensive |
Brand Reputation Concerns | Moderate | Some significant legal controversies | Minimal to none |
Cost | Premium | Premium | Premium |
Commitment Time for Results | Weeks to months | Months, with variable results | Weeks, consistent use recommended |
User Feedback | Some positive citing modest improvements | Mixed, with some users citing minimal effects | Predominantly positive |
Ingredients' Transparency | Fully disclosed | Mostly disclosed but with opaque proprietary ingredient (Apoaequorin) | Fully disclosed |
Dosage Convenience | 4 capsules daily | 1 capsule daily | 3 capsules daily |
Servings Per Container | 15 | 30 | 30 |
Potential Side Effects | Low risk | Low to moderate risk | Low risk |
Customer Support & Return Policy | Good, with return options | Mixed reviews on customer service; return policy varies | Excellent with money-back guarantee |
Product Availability | Widely available | Widely available but some regional restrictions | Available through official site only |
Additional Benefits | None | Potentially improved sleep for some users | Boosts neurotransmitters, enhanced neuroprotection |
What are Nootropics?
The need for nootropics arises from the increasingly demanding environments we find ourselves in. The digital age, with its plethora of distractions and rapid information exchange, often leaves us mentally exhausted [1]. Balancing work, family, health, and personal growth can feel like juggling too many balls, with the ever-present fear of dropping one. Consequently, mental sharpness, focus, and adaptability become essential assets in daily life. Furthermore, as life expectancy increases, so does our desire to maintain cognitive health throughout our lifespans, ensuring not just longevity but also a high quality of life [2]. Nootropics, therefore, are sought not just by those wanting an immediate boost but also by those aiming for long-term brain health [3].
Coined by Dr. Corneliu Giurgea in 1972, the term 'nootropic' amalgamates the Greek words 'nous' (mind) and 'trepein' (to turn or bend), symbolizing their ability to 'bend the mind' [4]. Nootropics encompass a diverse array of compounds, from natural herbs and vitamins, as seen in products like Focus Factor, to synthesized substances. These agents, when consumed, aim to enhance cognitive functions such as memory, attention, creativity, and even mood [5].
The Need For Nootropics
Today's world presents a unique concoction of cognitive challenges. Unrelenting streams of information, multitasking demands, and incessant technological stimuli have collectively burgeoned the stress on our cognitive apparatus [6]. Add to this mix the natural cognitive decline due to aging, and there emerges a pressing need to bolster the brain's resilience [7].
Nootropics like Focus Factor, which encompasses an array of vitamins, amino acids, and herbal extracts, and Prevagen, with its unique ingredient Apoaequorin, cater to this demand by offering potential neural support and enhancement [8].
Comparing Focus Factor vs Prevagen
Focus Factor: Optimizing Brain Performance
Focus Factor, over the years, has emerged as a prominent nootropic contender in the cognitive enhancement sphere. Branding itself as a comprehensive supplement for brain health, it integrates an array of vitamins, minerals, and herbal ingredients designed to synergistically augment cognitive faculties [9].
Focus Factor Ingredients and How They Work
Vitamin A (1083.32mcg), Vitamin D (2.5mcg), Vitamin E (20.16mg), Vitamin C (250 mg), Thiamin (Vitamin B1) (3mg), Riboflavin (Vitamin B2) (1.7mg), Niacin (Vitamin B3) (25mg), Vitamin B6 (7mg), Folic acid (Vitamin B9) (400mcg), Vitamin B12(20mcg), Biotin (Vitamin B7) (300mcg), Pantothenic acid (Vitamin B5) (12mg), Calcium (200mg), Iron (5mg), Magnesium (100mg), Zinc (10mg), Copper(400mcg), Manganese (2mg), Selenium (50mcg), Chromium (100mcg), Molybdenum (10mcg), Iodine (22.5mcg), Ginkgo Biloba (3000mg), Grape Seed (1500mg), Korean Ginseng (750 mg), Bilberry (500 mg), L-Tyrosine (as N-Acetyl L-Tyrosine) (500mg), Dimethylaminoethanol Bitartrate (DMAE) (100mg), L-Choline (as Bitartrate) (75mg), L-Glutamine (50mg), Inositol(25mg), L-Alpha Glycerophosphorylcholine (Alpha GPC) (20mg), Algae Oil Powder (10mg), Boron (as Di Sodium Tetraborate) (10mg)
The unique fusion of ingredients in Focus Factor aims to address multiple facets of cognitive function. Vitamins like Vitamin A, C, D, and the B-complex promote overall neural health and neurotransmitter synthesis [10]. Minerals such as zinc, magnesium, and selenium serve pivotal roles in neuron signaling and protection [11].
Moreover, herbs like Ginkgo Biloba and Korean Ginseng have historical backgrounds in traditional medicine for enhancing memory and concentration [12]. Recent scientific explorations have reinforced their efficacy. For instance, Ginkgo Biloba is suggested to increase blood flow to the brain, potentially improving cognitive speed and attention [13]. Amino acids, including L-Tyrosine and L-Glutamine, further cater to neurotransmitter synthesis and neuronal health [14].
Focus Factor Pros and Cons
Pros:
- Evidence-based Composition: Contains ingredients supported by scientific literature.
- Potential Cognitive Boost: Designed to enhance mental faculties, particularly memory.
- Dietary Flexibility: Accommodates both vegetarian preferences and gluten-free requirements.
Cons:
- Suboptimal Dosages: Many ingredients are not be present in their optimal quantities.
- Digestive Concerns: There's a chance of experiencing gastrointestinal disturbances.
- Variable Results: May not deliver consistent benefits across all individuals.
- Research Scope: There's a limited breadth of clinical research confirming its overall efficacy.
Prevagen: Unique Use of Apoaequorin
Prevagen Ingredients and How They Work
Vitamin D (50mcg), Apoaequorin (10mg)
Prevagen's formula significantly differentiates itself in the nootropic market, primarily due to its utilization of Apoaequorin. Apoaequorin, originally derived from a species of jellyfish, is believed to support cognitive function and assist in maintaining healthy brain cells [15]. This protein, when introduced to calcium, emits a blue-green light, leading scientists to investigate its potential implications in calcium regulation within brain cells [16].
Prevagen also incorporates Vitamin D, an essential vitamin that plays a pivotal role in several bodily functions. The brain has numerous Vitamin D receptors, and a deficiency can potentially contribute to cognitive decline [17]. Thus, the combination of Vitamin D and Apoaequorin suggests that Prevagen targets both neuron health and general cognitive support.
What Is Apoaequorin?
Apoaequorin is a fascinating protein, originally discovered in a particular species of jellyfish known as Aequorea victoria. This jellyfish, primarily found in the Pacific Northwest, emits a mesmerizing blue-green luminescence, which is caused by the reaction between Apoaequorin and calcium ions [18].
Delving into the science, when Apoaequorin binds to calcium, it undergoes a molecular transformation which results in the emission of this characteristic blue-green light. This light emission is a process referred to as bioluminescence [19]. Given its ability to detect calcium, researchers became intrigued by the potential applications of Apoaequorin, especially in understanding cellular calcium dynamics, which play a critical role in numerous cellular processes in organisms, including humans.
In the context of human health, Apoaequorin has garnered attention for its potential benefits in supporting cognitive function. The premise here is the idea that calcium dysregulation in the brain is associated with aging and age-related cognitive decline. As a result, Apoaequorin, with its calcium-binding properties, is theorized to help in maintaining optimal calcium levels in brain cells [20].
Apoaequorin has made its way into dietary supplements, most notably Prevagen, which is marketed to support memory and overall cognitive function. However, while the potential of Apoaequorin is promising, it's essential to approach its benefits with a discerning eye, as the breadth of clinical research on its effectiveness in humans remains in the early stages [21].
Prevagen Pros And Cons
Pros:
- Distinct Ingredient: Apoaequorin is a unique addition not commonly found in other nootropics, suggesting specialized brain cell support.
- Vitamin D's Neuroprotection: Its inclusion can combat potential cognitive decline due to vitamin D deficiency [22].
- Simplified Formula: A concise list of ingredients ensures targeted action and reduces potential ingredient interactions.
Cons:
Our Experiences With Focus Factor vs Prevagen
Our Experience with Focus Factor
In search of enhancing our cognitive performance, we embarked on a journey to understand and to evaluate Focus Factor's efficacy for ourselves.
After several days of taking Focus Factor, we did notice some modest improvements in cognitive faculties. The increased clarity in thought processes can be attributed to the presence of ingredients like Ginkgo Biloba, renowned for its ability to improve blood flow to the brain [24]. Meanwhile, the blend of B vitamins, including B6, B12, and Folic Acid, can bolster neurochemical synthesis and promote healthy nerve cell communication [25]. The inclusion of Alpha GPC, although in a comparatively lesser dosage, has been linked to potential enhancements in memory and cognitive speed [26].
Yet, when benchmarking our experience with Focus Factor against other scientifically-formulated nootropics, particularly our current favorite, NooCube, it felt a tad underwhelming. NooCube boasts an impressive lineup like L-theanine and L-tyrosine, which are known for promoting relaxation without sedation and counteracting stress effects, respectively [27]. The presence of Bacopa Monnieri in NooCube, a well-researched adaptogen, has strong credentials for enhancing memory and cognitive performance [28].
The experience with Focus Factor was not transformative, but it did provide some level of cognitive lift. However, the enhancement was not as pronounced or as sustained as what we experienced with more precision-engineered products like NooCube.
While the wide array of vitamins and minerals in Focus Factor contributes to overall wellness, one might ponder whether they are at optimal dosages for pronounced nootropic effects. Some ingredients, although beneficial in general health contexts, might not offer substantial cognitive enhancements in the dosages present.
Focus Factor provided some cognitive benefits, possibly due to its diverse ingredient list, but it didn't quite hit the benchmark when compared to more scientifically calibrated nootropics.

Our Experience With Prevagen
With the promise of better cognitive function, we embarked on the journey of trying Prevagen. The primary selling point of this supplement revolves around its unique ingredient, Apoaequorin. Naturally, our curiosity led us to assess its potential advantages personally.
The experience with Prevagen was subtle, almost elusive. Over the duration, we perceived a faint elevation in cognitive function. The presence of Vitamin D, essential for various brain processes and overall neurological health [29], could be a contributor. However, the star ingredient, Apoaequorin, which is a calcium-binding protein originating from certain species of jellyfish [30], is believed to support memory function. Its mode of action, as suggested, revolves around its potential in managing intracellular calcium levels [31], which plays a vital role in neuronal health and function.
Yet, when pitted against the effects observed with scientifically backed nootropics, especially our current favorite, NooCube, Prevagen's impact felt very modest by comparison. NooCube's includes ingredients like Bacopa Monnieri, well-documented for its memory-enhancing properties [32], and Huperzine A, known for increasing levels of neurotransmitters in the brain [33]. Compared to this robust concoction, the effect of Prevagen, for us, remained on the periphery of discernment.
In trying to ascertain the reasons behind the modest effects of Prevagen, one might hypothesize that the simplistic formulation, with a spotlight on Apoaequorin, might not provide the synergistic multi-faceted approach seen in more comprehensive nootropic stacks.
To put it succinctly, while Prevagen did induce a minimal uptick in cognitive performance, it was not as vivid or tangible as one might expect from a product championing cognitive enhancement. The world of nootropics is vast, with various formulations vying for attention. In our journey, Prevagen’s whisper of cognitive improvement was overshadowed by the articulate benefits echoed by other scientifically-formulated supplements like NooCube.

Brand Reputation and Legal Considerations
When selecting a nootropic, the reputation and legal standing of the brand play pivotal roles in making an informed choice. Let's delve into two such brands, Focus Factor and Prevagen, and their respective market stances.
Focus Factor's Market Stand and Legal History
Focus Factor, with its comprehensive ingredient list, has positioned itself as a multi-faceted cognitive supplement. However, like many brands in the supplement industry, it has not been devoid of scrutiny. There have been instances where the brand faced challenges regarding the veracity of its marketing claims [34]. These revolved around the emphasis on the scientific backing of its formula and its advertised cognitive benefits. While some of these challenges have been addressed, potential users should remain astute and cross-reference product claims with independent scientific findings. Nevertheless, Focus Factor continues to maintain a sizeable market share.
Prevagen's Brand Reputation and Litigations
Prevagen's journey in the market has been noteworthy. Its unique selling proposition, Apoaequorin, has generated both intrigue and skepticism. The brand found itself in the limelight when concerns arose about its memory-enhancement claims [35]. These led to legal actions, primarily focusing on the assertion that the ingredient, Apoaequorin, was clinically proven to assist in memory improvement [36].
Side-by-Side Comparison of Focus Factor and Prevagen
Efficacy and Clinical Backing
Focus Factor has a more extensive ingredient list, with ingredients like Ginkgo Biloba and L-Tyrosine known to support cognitive functions [37]. Its approach is to provide a spectrum of nutrients, targeting various cognitive aspects. Scientifically, some ingredients have substantial research behind them; however, the synergy of such an extensive blend remains less documented and many ingredients are dosed below clinically proven levels.
Prevagen, on the other hand, uniquely offers Apoaequorin, a protein initially derived from certain jellyfish. While there have been claims about its memory-enhancing properties, robust independent clinical studies are somewhat limited [38].
Side Effects and Safety
Focus Factor, given its broad spectrum of ingredients, may pose a risk of interactions, especially for individuals already on medication [39]. Common side effects could include digestive discomfort, especially if taken without food.
Prevagen's primary ingredient, Apoaequorin, has been touted as safe, but there have been instances of headaches, dizziness, or heart palpitations in some users [40].
Both supplements recommend consulting a healthcare professional before usage, especially for those with pre-existing conditions or on other medications.
Cost and Value for Money
Financially speaking, Focus Factor offers a multitude of ingredients in one package, which might seem cost-effective for those seeking a broad approach. The price per serving is generally less than Prevagen.
Prevagen, with its specialized formulation, comes at a higher cost per serving. Its value proposition lies in its unique offering of Apoaequorin, which is absent in most nootropics [41].
In the realm of value for money, the decision between the two boils down to individual preference: a comprehensive approach with Focus Factor or a specialized one with Prevagen.
Testimonials and Real-life Feedback
The consumer landscape today is dominated not only by clinical trials and scientific research but equally by firsthand user experiences. Reviews, testimonials, and feedback provide invaluable insights into the efficacy, safety, and overall satisfaction with products. Let's delve into the real-life feedback on Focus Factor and Prevagen.
Focus Factor Reviews
Feedback for Focus Factor often revolves around effects on focus. Users frequently report feeling heightened alertness and improved memory [42]. Some appreciate the "all-in-one" nature of the supplement, negating the need to buy multiple products. However, a few users noted initial digestive discomfort, which subsided when taken with meals. While many testimonials lean positive, some consumers didn't observe any significant cognitive improvements, underscoring the variability of individual responses [43].
Prevagen Reviews
Prevagen, with its unique ingredient Apoaequorin, has its own set of dedicated users. Many users laud the product for its role in enhancing memory, especially senior users [44]. The clear and targeted formulation appeals to those looking for specific cognitive support without additional ingredients. Nevertheless, there are a large number of users who experienced minimal benefits, while a smaller subset reported transient side effects like headache [45]. As with any supplement, the reviews highlight the spectrum of individual experiences, suggesting that efficacy can be influenced by personal health nuances.
Both Focus Factor and Prevagen have their loyal customer base, but they also both have a large number of reviews citing negative feedback or very limited results.
Overall Results
Focus Factor
Overall Rating

Prevagen
Overall Rating

- Focus Factor Does a Few Things Well, But Overall It's A Basic Offering: Limited range and level of benefits, often not meeting broad cognitive needs. Many ingredients are dosed below clinically effective levels.
- Prevagen Lacks Scientific Evidence And Results Were Disappointing: In our testing, most users reported no discernable cognitive improvement after consistent usage. Prevagen's ingredient profile is very limited and lacks many clinically proven cognitive enhancing ingredients. Instead, it relies on Apoaequorin, an ingredient lacking in robust scientific evidence for its effectiveness as a cognitive enhancer.
- Recommended Alternative: In our testing, NooCube outperformed Focus Factor and Prevagen in all areas. Its more comprehensive formulation is backed by scientific evidence, and we found it offered a far greater level of improvement to focus, cognitive performance and memory.
NooCube
Overall Rating

Overall Verdict
After extensive review and firsthand experience with Focus Factor, Prevagen, and NooCube, our findings paint a clear picture. Both Focus Factor and Prevagen, despite having unique formulations, present certain restrictions in terms of cognitive enhancement and ingredient variety [46,47]. Focus Factor, with its extensive list of ingredients, only tackles a narrow range of cognitive functions and lacks clinically effective dosages for many ingredients. Prevagen ingredient list focuses primarily on Apoaequorin, potentially sidelining the comprehensive benefits a more varied ingredient list could offer [48].
NooCube, however, stands out in several significant ways. Its ingredient list, which includes ingredients like Bacopa Monnieri, Huperzine A, and Pterostilbene, among others, is both robust and grounded in scientific literature [49]. Our team's direct experiences mirrored the research; we noticed enhanced cognitive function, improved focus, and better memory retention with NooCube compared to the other two products. The inclusion of compounds like L-theanine and L-tyrosine, which have been studied for their potential to improve cognitive performance under stress, further bolster NooCube's comprehensive approach to cognitive health [50].
Taking into account both empirical research and our firsthand experiences, NooCube is our preferred nootropic. For those in pursuit of a reliable, science-grounded brain supplement, NooCube is our top recommendation.
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